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Fig. 4 | Human Genomics

Fig. 4

From: The complex impact of cancer-related missense mutations on the stability and on the biophysical and biochemical properties of MAPK1 and MAPK3 somatic variants

Fig. 4

Near-UV CD of non-phosphorylated (NP-) and phosphorylated (P-) MAPK1 and MAPK3 group I and group II variants. Near-UV CD spectra of NP-MAPK1 (A, dashed line), NP-MAPK3 (C, dashed line), P-MAPK1 (B, continuous line) and P-MAPK3 variants (D, continuous line), were monitored at 1.3 mg/mL protein concentration in 20 mM Tris–HCl pH 7.5, 1.0 mM DTT, 0.1 M NaCl, in a 1.0-cm quartz cuvette

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Human Genomics

ISSN: 1479-7364