Fig. 1
From: Epigenomic signature of major congenital heart defects in newborns with Down syndrome
Global hypomethylation in DS-CHD males versus DS non-CHD males is driven by samples with high nRBC proportions. Density plot of average percent smoothed methylation in DS-CHD (Yes: blue) and DS non-CHD (No: red) in A females (note that red and blue lines are overlapping) and B males. Percent global methylation correlated with nRBC proportion in C females (Pearson’s r =  − 0.93, p = 2.16E−24) and D males (Pearson’s r =  − 0.84, p = 2.13E−9)