Fig. 4
From: FGFR1 variants contributed to families with tooth agenesis
a Heatmap showing the expression levels of transcripts in samples from the FGFR1 overexpression and control groups. Red color refers to upregulation, and blue color refers to downregulation of gene transcription. b Volcano plot of differentially expressed genes. Purple dots represent down-regulated genes, and turquoise dots represent up-regulated genes. c KEGG pathway analysis ranked the top 20 KEGG pathways (|log2FC|≥ 1 and p ≤ 0.05). d Protein levels of pathway genes were assayed in the cells transfected by control, wildtype and mutation lentivirus by western blot