Table 1 Summary of gynecological diseases and hormonal treatments in the study family
From: Whole-exome sequencing reveals candidate high-risk susceptibility genes for endometriosis
Individual | Endometriosis (age at dg) | HGSC (age at dg) | Uterine leiomyoma (age at dg) | Hormonal treatments |
|---|---|---|---|---|
I-2 | Not known | No | Suspected | Not known |
II-2 | Ovarian (24) | Stage IIIC (50) | Multiple (35) | Oral progestin |
II-3 | Ovarian (25) | Stage I (46) | No | No |
III-1 | Ovarian, peritoneal (24) Deep (29) | No | One (29) | Oral progestins, LNG-IUS, and GnRH analog injections |
III-2 | Peritoneal (23) Ovarian, deep (25) Suspected adenomyosis (25) | No | No | Oral progestins, GnRH analog injections, LNG-IUS, and combination oral contraceptive (continuous) |