Fig. 4

Performance assessment of the integrated model. Proportions of hepatocytes, cholangiocytes, liver sinusoidal and portal endothelial cells were integrated with gene markers described in the literature. The resulting integrated model was trained with Roskams-Hieter et al. (2022) dataset and tested on the remaining datasets. The results were assessed with receiver operator characteristic (ROC) curves and area under ROC curves (AUC) values (A), a confusion matrix (B) and were compared with the performance of other models (C). The error bars depicted in the figure represent the 95% confidence intervals