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Fig. 1 | Human Genomics

Fig. 1

From: ANXA1 is identified as a key gene associated with high risk and T cell infiltration in primary sclerosing cholangitis

Fig. 1

Identification of DEGs between PSC and HC in the GSE159676 dataset. A PCA map of GSE159676. B Volcano map of all DEGs analyzed by the limma package in R language; an adjusted p value < 0.05 and a | log2 FC |≥ 1 were considered threshold values for significant DEGs. C Heatmap of the top 50 DEGs, including the top 25 upregulated and the top 25 downregulated genes in PSC. DEGs, differentially expressed genes; PSC, primary sclerosing cholangitis; HC, healthy control; PCA, principal component analysis

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