Fig. 2

Untargeted plasma metabolomics analyses of SARS-CoV-2-infected and uninfected subjects. A Results of univariate analysis of the metabolites are shown for SARS-CoV-2-negative subjects (HCW black square), SARS-CoV-2-positive patients who during their hospitalization did not require any external oxygen supply or required only a low flow of oxygen (Class 1, red square), SARS-CoV-2-positive patients who required a high flow of oxygen (Class 2, green square), and SARS-CoV-2-positive patients who needed positive airway pressure (biphasic; BIPAP or continuous; CPAP) or were intubated (Class 3, blue square). B Univariate analysis of the identified metabolites in the plasma showing differences in the metabolome between SARS-Cov-2 infected patients who survived (black square) and those who did not survive (red square). Data are presented as the mean ± SD; dots outside the box plot are in the upper quartile (75th percentile) of the distribution and the dots inside the box plot are in the interquartile range (IQR), where 50% of the data are located. Outside the box plot are the patients that are outside the IQR range, and the box plot is divided at the median. Student’s unpaired t-test, NS (non-significant)  (color figure online)