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Table 1 Patient summary by histopathology and clinical factors

From: Total RNA sequencing reveals gene expression and microbial alterations shared by oral pre-malignant lesions and cancer

 

Histopathology group

Characteristic

Control N = 18 (27%)1

Hyperkeratotic; Not Reactive (HkNR) N = 17(26%)1

Dysplasia N = 22 (33%)*

OSCC N = 9(14%)1

Age

66 (51,73)

67 (30, 81)

66 (44, 92)

68 (49, 80)

Sex

    

  Female

11 (61%)

11 (65%)

11 (50%)

5 (56%)

  Male

7 (39%)

6 (35%)

11 (50%)

4 (44%)

Race

    

  Asian

0 (0%)

0 (0%)

1 (14%)

0 (0%)

  Black

2 (18%)

0 (0%)

1 (14%)

0 (0%)

  White

9 (82%)

2 (100%)

5 (71%)

3 (100%)

  Unknown

7

15

15

6

Smoking_status

    

  No

11 (69%)

7 (54%)

10(53%)

7 (88%)

  Yes

5 (31%)

6 (46%)

9 (47%)

1 (12%)

  Unknown

2

4

3

1

Alcohol status

  Current

14(88%)

9 (69%)

13(72%)

4 (50%)

  Former

0 (0%)

0 (0%)

3(17%)

1 (12%)

  Never

2 (12%)

4 (31%)

2 (11%)

3 (38%)

  Unknown

2

4

4

1

Progression status

  Stable

7 (70%)

5(71%)

3 (38%)

2 (100%)

  Progressed to dysplasia

1 (10%)

2 (29%)

2 (25%)

0 (0%)

  Progressed to SCC

2 (20%)

0 (0%)

3 (38%)

0 (0%)

  Unknown

8

10

14

7

  1. Biopsy from patients (n = 66) are separated into four histopathology groups and segregated by age, smoking, and disease progression status
  2. 1Median (Range); n (%)