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Fig. 1 | Human Genomics

Fig. 1

From: Transcriptome and proteome analysis reveals the anti-cancer properties of Hypnea musciformis marine macroalga extract in liver and intestinal cancer cells

Fig. 1

Cytotoxicity and cell death measurements after Hypnea musciformis extract (HME) treatment. Dose-dependent inhibition of HME against A Ls174 intestinal and B HepG2 liver cancer cell proliferation. IC50 values are indicated for each cell line. Cytotoxicity was evaluated using XTT assay. Each point represents mean value ± SD. C Flow cytometry analysis of Ls174 cells stained with Annexin V-PE and 7-AAD, highlighting the percentage of viable, early and late apoptotic and necrotic cells after treatment with HME for 0.5, 1, 2 4, 8, 16 and 24 h, respectively. Each bar represents mean value ± SD. Dashed line demonstrates the change of apoptotic cells as percentage compared to the untreated control. D Same as in C but for HepG2 cells. E Effect of HME on mitochondrial membrane potential (MMP) in Ls174 cells. Each bar represents mean value ± SD. Line demonstrates the change of MMP as percentage compared to the untreated control. F Same as in E but for HepG2 cells. Asterisk marks statistical significance (p < 0.05) in all panels

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Human Genomics

ISSN: 1479-7364