Fig. 2

Mitochondrial mass is unchanged between ALS and controls. a–c Mitochondrial mass was determined by mtDNA copy number comparing the D-loop sequence to the single copy gene B2M for whole blood a and white blood cells (WBC), b, respectively. c mtDNA copy number of denucleated platelets (PLT) is shown as Cq value. d–f As a second marker for mitochondrial mass the citrate synthase activity was determined in whole blood d, WBC e and PLT f and displayed as (μmol*µg)/min. (Data is illustrated as mean ± SD, Kruskal–Wallis test with Dunn’s correction, *p ≤ 0.05). CTRL Control, non-mat Non-maternal ALS, mat Maternal ALS