Fig. 6

A Distribution of mutations in CDC27, PIK3CA, and TP53 genes in Caucasians and African American patients are represented here. Green squares within the matrix indicate Co-occurrence, and the brown squares indicate mutual exclusivity across genes. The color scheme indicates the strength of the association, with darker colors indicating stronger co-occurrence or mutual exclusivity between the genes. B, C Reported TCGA drivers identified in Caucasians and African American patients are represented here. Yellow squares indicate if the gene was identified as an oncogenic driver. C, D Unique mutational signatures identified in Caucasians and African American patients