Fig. 4

Distribution of mutations and representations of mutational interactions across histological subgroups. A Distribution of CHD1, PTCH1, and TP53 mutations across the histological subtypes. B, C, D Mutational interactions identified across mutations in IDC, ILC, and Other. Green squares within the matrix indicate Co-occurrence, and the brown squares indicate mutual exclusivity across genes. The color scheme indicates the strength of the association, with darker colors indicating stronger co-occurrence or mutual exclusivity between the genes