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Table 4 Association of smoking-related miRNAs with incident lung cancer

From: Smoking-related dysregulation of plasma circulating microRNAs: the Rotterdam study

miRNA

HR

95% CI

P-value

miR-1915-3p

0.47

0.24–0.90

0.024

miR-146b-5p

6.1

1.48–25.14

0.012

miR-6085

0.56

0.33–0.94

0.030

miR-6769b-3p

5.61

1.20–26.18

0.028

miR-10a-5p

2.67

1.29–5.52

0.008

let-7c-5p

3.93

1.19–12.94

0.024

miR-100-5p

2.22

1.19–4.12

0.012

miR-149-3p

1.58

1.08–2.31

0.018

  1. This table shows the results for the Cox proportional hazards regression adjusted for age, sex, cohort, smoking, chronic disease, BMI, RBC, WBC, alcohol, and education
  2. Hazard ratios (HRs) are reported for each log2 unit increase in miRNA level in the longitudinal setting