Table 3 ACE2 SNPs and ACE1 rs1799752 (I/D) genotypes association with SARS-CoV-2 variants
Variants | rs2074192 Genotypes | Recovered patients | Deceased patients | OR (95% CI) |
|---|---|---|---|---|
Alpha | C/C | 437 | 307 | 1.00 |
|  | C/T | 162 | 128 | – |
|  | T/T | 164 | 197 | 1.79 (1.39–2.31) |
Delta | C/C | 314 | 323 | 1.00 |
|  | C/T | 98 | 190 | 2.16 (1.59–2.94) |
|  | T/T | 100 | 400 | 3.94 (3.01–5.16) |
Omicron BA.5 | C/C | 604 | 225 | 1.00 |
|  | C/T | 212 | 95 | 1.39 (1.02–1.89) |
|  | T/T | 216 | 158 | 2.06 (1.59–2.67) |
Variants | rs1978124 Genotypes | Recovered patients | Deceased patients | OR (95% CI) |
|---|---|---|---|---|
Alpha | T/T | 484 | 381 | 1.00 |
|  | T/C | 83 | 113 | 2.08 (1.50–2.88) |
|  | C/C | 196 | 138 | – |
Delta | T/T | 302 | 616 | 1.00 |
|  | T/C | 74 | 62 | – |
|  | C/C | 136 | 235 | – |
Omicron BA.5 | T/T | 547 | 209 | 1.00 |
|  | T/C | 247 | 199 | 2.62 (2.00–3.43) |
|  | C/C | 238 | 70 | – |
Variants | rs2285666 Genotypes | Recovered patients | Deceased patients | OR (95% CI) |
|---|---|---|---|---|
Alpha | C/C | 299 | 532 | 1.00 |
|  | C/T | 295 | 28 | – |
|  | T/T | 169 | 72 | – |
Delta | C/C | 265 | 585 | 1.00 |
|  | C/T | 20 | 255 | 5.77 (3.58–9.30) |
|  | T/T | 227 | 73 | – |
Omicron BA.5 | C/C | 292 | 278 | 1.00 |
|  | C/T | 620 | 127 | – |
|  | T/T | 120 | 73 | – |
Variants | rs1799752 (I/D) Genotypes | Recovered patients | Deceased patients | OR (95% CI) |
|---|---|---|---|---|
Alpha | D/D | 216 | 258 | 1.00 |
|  | I/D | 352 | 275 | – |
|  | I/I | 195 | 99 | – |
Delta | D/D | 152 | 387 | 1.00 |
|  | I/D | 178 | 409 | 0.25 (0.19–0.34) |
|  | I/I | 182 | 117 | – |
Omicron BA.5 | D/D | 158 | 215 | 1.00 |
|  | I/D | 599 | 179 | – |
|  | I/I | 275 | 84 | – |