Table 1 List of top cis-eQTLs for 29 miRNAs associated with one of the 8 blood phenotypes correlated with ICU admission

rs34088055

hsa-miR-5189-5p

Chr16:88469262

T

1.70E-16

296

Neutrophil count

rs7501512

hsa-miR-6868-3p

Chr17:76097225

A

2.10E-12

794

D-dimers

rs1031034

hsa-miR-1255a

Chr4:101302229

A

2.18E-10

28,136

D-dimers

rs2925983

hsa-miR-7854-3p

Chr16:81533035

C

5.96E-07

907

D-dimers

rs12447180

hsa-miR-5189-3p

Chr16:88451314

C

4.42E-06

17,670

Neutrophil count, D-dimers

rs28370965

hsa-miR-4999-5p

Chr19:8408107

T

9.60E-06

18,747

C-reactive protein

rs9914549

hsa-miR-4525

Chr17:82667081

G

7.41E-05

1200

Lymphocyte count

rs1765566

hsa-miR-3675-5p

Chr1:16708741

T

8.44E-05

150,247

Interleukin-6

rs77318922

hsa-miR-7976

Chr3:127757054

C

8.64E-05

169,878

C-reactive protein

rs9364148

hsa-miR-30a-3p

Chr6:71277249

A

0.000146

126,305

Urea

D-dimers

rs1434282

hsa-miR-181a-3p

Chr1:199041592

C

1.65E-04

182,502

D-dimers

rs11569501

hsa-miR-3940-3p

Chr19:6691620

A

1.03E-03

275,165

C-reactive protein

rs76321536

hsa-miR-636

Chr17:76976432

G

0.001286

239,944

D-dimers

rs79260648

hsa-miR-576-3p

Chr4:109205695

C

4.06E-03

283,057

Urea

Neutrophil count, Neutrophil-to-lymphocyte ratio

rs1256522

hsa-miR-625-3p

Chr14:65271311

C

0.004111

199,842

Neutrophil count, Neutrophil-to-lymphocyte ratio

rs1997243

hsa-miR-339-3p

Chr7:1044141

G

0.00711

21,164

C-reactive protein

rs7710462

hsa-miR-5003-3p

Chr5:172643217

G

0.007797

19,005

C-reactive protein, Neutrophil-to-lymphocyte ratio

rs60095937

hsa-miR-3177-3p

Chr16:1732963

A

0.009533

2075

D-dimers

rs941449

hsa-miR-6777-3p

Chr17:17746517

C

0.01199

66,963

C-reactive protein, D-dimers, ICU admission

rs4756822

hsa-miR-6073

Chr11:15695412

T

0.01375

274,143

C-reactive protein, D-dimers

rs2495972

hsa-miR-1275

Chr6:33964665

G

0.0181

35,353

Lymphocyte count

rs11768761

hsa-miR-339-5p

Chr7:1030171

G

0.02617

7159

Urea

rs59088240

hsa-miR-342-5p

Chr14:99827961

A

0.02867

281,712

C-reactive protein, Neutrophil-to-lymphocyte ratio, D-dimers

rs2382817

hsa-miR-6810-3p

Chr2:218286495

C

0.03112

55,463

Interleukin-6, D-dimers

rs9787810

hsa-miR-7155-5p

Chr11:64317826

T

0.0337

24,060

Neutrophil count, D-dimers

rs1499294

hsa-miR-4742-3p

Chr1:224564806

C

0.04451

166,557

D-dimers

rs62130995

hsa-miR-4746-5p

Chr19:4460286

A

0.0462

14,277

D-dimers, ICU admission

rs4144630

hsa-miR-181a-2-3p

Chr9:124676921

T

0.04954

15,597

Chloride, Lymphocyte count