Table 2 TRIM22 rs1063303, rs7935564, and rs7113258 association with COVID-19 mortality

Allele

C

618 (62.3%)

396 (39.9%)

–

–

–

–

G

376 (37.7%)

594 (60.1%)

–

–

–

–

Codominant

C/C

197 (39.6%)

69 (13.9%)

1.00

 < 0.0001*

1279.0

1293.7

C/G

224 (45.1%)

258 (52.1%)

3.29 (2.37–4.56)

G/G

76 (15.3%)

168 (33.9%)

6.31 (4.29–9.28)

Dominant

C/C

197 (39.6%)

69 (13.9%)

1.00

 < 0.0001*

1293.0

1302.8

C/G-G/G

300 (60.4%)

426 (86.1%)

4.05 (2.97–5.54)

Recessive

C/C–C/G

421 (84.7%)

327 (66.1%)

1.00

 < 0.0001*

1331.8

1341.6

G/G

76 (15.3%)

168 (33.9%)

2.85 (2.09–3.87)

Overdominant

C/C-G/G

273 (54.9%)

237 (47.9%)

1.00

0.026*

1374.3

1384.1

C/C

224 (45.1%)

258 (52.1%)

1.33 (1.03–1.70)

Minor allele frequency (G)

0.38

0.6

–

–

–

–

Allele

A

708 (71.4%)

337 (34.0%)

–

–

–

–

G

286 (28.6%)

653 (66.0%)

–

–

–

–

Codominant

A/A

261 (52.5%)

89 (18%)

1.00

 < 0.0001*

1148.3

1163.0

A/G

186 (37.4%)

159 (32.1%)

2.51 (1.82–3.45)

G/G

50 (10.1%)

247 (49.9%)

14.49 (9.83–21.35)

Dominant

A/A

261 (52.5%)

89 (18%)

1.00

 < 0.0001*

1245.3

1255.1

A/G-G/G

236 (47.5%)

406 (82%)

5.05 (3.78–6.74)

Recessive

A/A-A/G

447 (89.9%)

248 (50.1%)

1.00

 < 0.0001*

1178.9

1188.7

G/G

50 (10.1%)

247 (49.9%)

8.90 (6.33–12.53)

Minor allele frequency (G)

0.29

0.69

–

–

–

–

Allele

A

739 (74.5%)

377 (38.0%)

–

–

–

–

T

255 (25.5%)

613 (62.0%)

–

–

–

–

Codominant

A/A

294 (59.1%)

109 (22.0%)

1.00

 < 0.0001*

1174.4

1189.1

A/T

151 (30.4%)

159 (32.1%)

2.84 (2.08–3.88)

T/T

52 (10.5%)

227 (45.9%)

11.77 (8.11–17.10)

Dominant

A/A

294 (59.1%)

109 (22%)

1.00

 < 0.0001*

1233.2

1243.0

A/T-T/T

203 (40.9%)

386 (78%)

5.13 (3.88–6.77)

Recessive

A/A-A/T

445 (89.5%)

268 (54.1%)

1.00

 < 0.0001*

1216.4

1226.2

T/T

52 (10.5%)

227 (45.9%)

7.25 (5.17–10.16)

Minor allele frequency (T)

0.26

0.62

–

–

–

–