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Fig. 1 | Human Genomics

Fig. 1

From: Enhancer promoter interactome and Mendelian randomization identify network of druggable vascular genes in coronary artery disease

Fig. 1

Enrichment and enhancer-promoter mapping. A, B Tissue and pathway enrichment of CAD GWAS. C Heatmap representing the relative distance of ATAC-seq signal to enhancer-promoter anchor loops; correlation is the measure of the observed to expected relative distance to the query point. D, E Individual independent significant SNPs and 3D mapping in enhancer-promoter HiChIP; tracks represent genes, ATAC-seq, H3K27ac ChIP, 1D H3K27ac-HiChIP and arcs of significant loops; vertical bar represents the SNP of interest and mapped genes are in red

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Human Genomics

ISSN: 1479-7364