Table 5 Genotype/minor-allele frequency distributions of the ACAN, BGN, DCN and VCAN polymorphisms for shoulder disability categories
Gene | SNP | Genotype or allele | No–low (n = 188) | Moderate–high (n = 43) | p value |
|---|---|---|---|---|---|
ACAN | rs1126823 A>G | G/G | 30 (56) | 33 (14) | 0.870 (0.987) |
A/G | 46 (87) | 42 (18) | |||
A/A | 24 (45) | 26 (11) | |||
A | 47 (177) | 47 (40) | 1.000 | ||
rs1516797 T>G | G/G | 29 (54) | 26 (11) | 0.864 (0.802) | |
G/T | 45 (84) | 44 (19) | |||
T/T | 27 (50) | 30 (13) | |||
T | 49 (184) | 52 (45) | 0.633 | ||
rs2882676 A>C | A/A | 31 (58) | 29 (12) | 0.895 (0.861) | |
A/C | 46 (86) | 50 (21) | |||
C/C | 23 (43) | 21 (9) | |||
C | 46 (172) | 46 (39) | 1.000 | ||
BGN | rs1042103 G>A | G/G | 73 (137) | 72 (31) | 0.416 (0.401) |
A/G | 25 (46) | 21 (9) | |||
A/A | 3 (5) | 7 (3) | |||
A | 15 (56) | 17 (15) | 0.619 | ||
rs743641 A>T | A/A | 49 (92) | 42 (18) | 0.431 (0.442) | |
A/T | 42 (78) | 42 (18) | |||
T/T | 10 (18) | 16 (7) | |||
T | 30 (114) | 37 (32) | 0.247 | ||
rs743642 G>T | G/G | 54 (102) | 51 (22) | 0.101 (0.101) | |
G/T | 40 (75) | 33 (14) | |||
T/T | 6 (11) | 16 (7) | |||
T | 26 (97) | 33 (28) | 0.226 | ||
DCN | rs516115 C>T | T/T | 29 (54) | 30 (13) | 0.976 (0.888) |
C/T | 52 (97) | 51 (22) | |||
C/C | 20 (37) | 19 (8) | |||
C | 46 (171) | 44 (38) | 0.905 | ||
VCAN | rs11726 A>G | G/G | 30 (56) | 51 (22) | 0.024 (0.033) |
A/G | 53 (99) | 33 (14) | |||
A/A | 18 (33) | 16 (7) | |||
A | 44 (165) | 33 (28) | 0.069 | ||
rs2287926 G>A | G/G | 67 (125) | 54 (23) | 0.113 (0.118) | |
A/G | 28 (53) | 44 (19) | |||
A/A | 5 (10) | 2 (1) | |||
A | 19 (73) | 24 (21) | 0.301 | ||
rs309559 A>G | G/G | 27 (51) | 26 (11) | 0.662 (0.685) | |
A/G | 49 (92) | 44 (19) | |||
A/A | 24 (44) | 30 (13) | |||
A | 48 (180) | 52 (45) | 0.550 |