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Fig. 4 | Human Genomics

Fig. 4

From: Aberration of the modulatory functions of intronic microRNA hsa-miR-933 on its host gene ATF2 results in type II diabetes mellitus and neurodegenerative disease development

Fig. 4

Schematic representation of the a projected mechanism for the development of type II diabetes mellitus mediated by hyperinsulinemia and hyperglycemia by ATF2 target genes GNAS, MAP4K4, PRKACB, PRKCE, PEA15, and BDNF. b Putative regulatory circuitry for controlling type II diabetes mellitus by regulating ATF2 target genes MAP4K4, PRKCE, PEA15, BDNF, PRKACB, and GNAS by hsa-miR-933

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