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Fig. 3 | Human Genomics

Fig. 3

From: Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B

Fig. 3

Asf1b KO mice display mild dyserythropoiesis. a Complete blood count of blood samples from Asf1b KO mice and WT littermates. The red blood cell (RBC) counts, the mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH) are depicted on individual animals. The black bar is the mean. T test p value is indicated. b Left, bar graph depicting the flow cytometry analysis of the erythroid compartment in the bone marrow of Asf1b KO and WT littermates following the gating strategy of Socolovsky [42]. Right, dot plot depicting the basal percentage of megakaryocyte-erythroid progenitors in the bone marrow of Asf1B KO mice and WT littermates. The black bar is the mean. T test p value is indicated. c Bar graph depicting the flow cytometry analysis of the erythroid compartment in the spleen of Asf1b KO and WT littermates following the gating strategy of Socolovsky [42]

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