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Table 3 Association of each candidate SNP with incidence of PONV in all 255 patients

From: Long non-coding RNA MIR4300HG polymorphisms are associated with postoperative nausea and vomiting: a genome-wide association study

rs#

Gene

Variant

MAF

HWE

Genotypes

P

Alleles

P

Wild-type (case/con)

Hetero (case/con)

Homo (case/con)

Major (case/con)

Minor (case/con)

rs17796714

CARMN

G > A

0.31

0.86

25/97

22/86

10/15

0.08

72/282

42/116

0.12

rs13234328

TNRC18

G > A

0.23

0.36

37/112

16/79

4/7

0.18

90/303

24/93

0.59

rs1333114

PTPRD

G > A

0.37

0.92

29/72

24/94

4/32

0.07

82/238

32/158

0.02

rs11232965

MIR4300HG

T > C

0.42

0.44

29/58

20/99

8/41

0.01

78/215

36/181

0.007

  1. Incidences are presented as number
  2. rs# SNP identifier at dbSNP, MAF minor allele frequency, HWE p value of deviance from Hardy–Weinberg equilibrium, Hetero heterozygous mutant, Homo homozygous mutant, Major major allele, Minor minor allele, case patients with PONV, con patients without PONV, P p values in statistics