Table 9 Female results by disease state for GPC5, rs10492503. Significance for the PP case subgroup is suggestive only as cell counts fell below the minimum required for chi-squared testing (n < 5)
| Â | GPC5 | rs10492503 | ||||||
|---|---|---|---|---|---|---|---|---|
Polymorphism | Genotypes | Alleles | ||||||
Group | AA (%) | AT (%) | TT (%) | p | A (%) | T (%) | P | OR (95% CI) |
Female MS case | ||||||||
PP (n= 35) | 17 (48.6) | 16 (45.7) | 2 (5.7) | 0.3358 | 50 (71.4) | 20 (28.6) | 0.4847 | 0.81 |
SP (n= 40) | 9 (22.5) | 25 (62.5) | 6 (15.0) | 0.0087 | 43 (53.8) | 37 (46.2) | 0.030 | 1.75 |
RR (n= 85) | 27 (31.8) | 36 (42.4) | 22 (25.9) | 0.0245 | 90 (52.9) | 80 (47.1) | 0.0032 | 1.81 |
Total control (n= 132) | 64 (48.5) | 49 (37.1) | 19 (14.4) | – | 177 (67.1) | 87 (32.9) | – | – |
HapMap CEU (%) | 38.3 | 51.7 | 10 | Â | 64.2 | 35.8 | Â | Â |