Table 8 Results for GPC5, rs10492503. Corrected P values using the Benjimini-Hochberg (PBH) and Bonferroni (PBon) methods are presented below the uncorrected P value
| Â | GPC5 | rs10492503 | |||||||
|---|---|---|---|---|---|---|---|---|---|
Polymorphism | Genotypes | Â | Alleles | ||||||
Group | AA (%) | AT (%) | TT (%) | p (PBH, PBon) | HWE | A (%) | T (%) | P | OR (95% CI) |
MS total cases (n= 204) | 67 (32.8) | 98 (48.1) | 39 (19.1) | 0.016 (0.08, 0.128) | 0.767 | 232 (56.8) | 176 (43.2) | 0.0079 | 1.50 |
PP case (n= 53) | 24 (45.3) | 24 (45.3) | 5 (9.4) | 0.492 | Â | 72 (67.9) | 34 (32.1) | 0.781 | 0.94 |
SP case (n= 51) | 13 (25.5) | 31 (60.8) | 7 (13.7) | 0.0098 | Â | 57 (55.9) | 45 (44.1) | 0.0519 | 1.56 |
RR case (n= 100) | 30 (30) | 43 (43) | 27 (27) | 0.0067 | Â | 103 (52.5) | 97 (48.5) | 0.0006 | 1.87 |
Male (n= 44) | 14 (31.8) | 21 (47.7) | 9 (20.5) | 0.560 | Â | 49 (55.7) | 39 (44.3) | 0.299 | 1.42 |
Female (n= 160) | 53 (33.1) | 77 (48.1) | 30 (18.8) | 0.0286 | Â | 183 (57.2) | 137 (42.8) | 0.0148 | 1.52 |
Control (n= 164) | 78 (47.6) | 62 (37.8) | 24 (14.6) | Â | 0.052 | 218 (66.5) | 110 (33.5) | Â | Â |
HapMap CEU (%) | 38.3 | 51.7 | 10 | Â | Â | 64.2 | 35.8 | Â | Â |