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Table 4 Interaction analysis between recurrent implantation failure and coagulation factors in participants

From: Associations between microRNA (miR-25, miR-32, miR-125, and miR-222) polymorphisms and recurrent implantation failure in Korean women

 

miR-25 rs1527423 T > C

miR-32 rs7041716 C > A

miR-125a rs12976445 C > T

miR-222 rs34678647 G > T

PT (s)

TT

TC + TT

CC

CA + CC

TT

CT + TT

TT

GT + TT

 <12

1.000 (reference)

0.935 (0.526–1.665)

1.000 (reference)

1.433 (0.808–2.540)

1.000 (reference)

0.544 (0.295–1.005)

1.000 (reference)

1.135 (0.706–1.824)

 ≥12

7.560 (2.409–23.725)

N/A

13.175 (3.745–46.350)

N/A

5.946 (1.864–18.971)

N/A

5.515 (1.056–28.792)

13.269 (2.823–62.379)

aPTT (s)

 <33.8

1.000 (reference)

1.022 (0.578–1.808)

1.000 (reference)

1.211 (0.678–2.161)

1.000 (reference)

0.547 (0.295–1.016)

1.000 (reference)

1.108 (0.693–1.771)

 ≥33.8

1.574 (0.659–3.760)

0.440 (0.050–3.865)

1.393 (0.598–3.245)

0.957 (0.085–10.779)

1.103 (0.415–2.931)

1.242 (0.339–4.558)

0.621 (0.193–1.998)

5.123 (1.379–19.030)

PLT (×103/μl)

 <294

1.000 (reference)

0.741 (0.391–1.403)

1.000 (reference)

1.081 (0.573–2.037)

1.000 (reference)

0.629 (0.340–1.163)

1.000 (reference)

1.386 (0.853–2.254)

 ≥294

0.832 (0.375–1.845)

1.641 (0.610–4.420)

0.999 (0.471–2.121)

1.512 (0.506–4.521)

1.167 (0.571–2.384)

0.616 (0.161–2.360)

1.397 (0.578–3.380)

1.114 (0.445–2.791)

  1. Italicized text indicates significant P values. The upper quartile for PT, aPTT, and PLT was 12 s, 33.8 s, and 294 × 103 platelets/μl respectively
  2. AOR, adjusted odds ratio; aPTT, activated partial thromboplastin time; PLT, platelet count; PT, prothrombin time
  3. Data are expressed as AOR (95% CI)