Skip to main content

Table 5 Stratified analyses of the rs2151280 with lung cancer risk and NSCLC by age

From: Association between polymorphism in CDKN2B-AS1 gene and its interaction with smoking on the risk of lung cancer in a Chinese population

GenotypingLung cancer Non-small-cell lung cancer 
 Controls (%)Cases (%)OR (95%CI)P valueORª (95%CI)Pª valueCases (%)OR (95%CI)P valueORª (95%CI)Pª value
> 60           
TT95 (36.8)106 (40.9)1.00 (ref)   83 (38.1)1.00 (ref)   
TC117 (45.3)123 (47.5)0.942 (0.647–1.371)0.7560.922 (0.617–1.380)0.695110 (50.5)1.076 (0.726–1.594)0.7151.054 (0.690–1.611)0.807
CC46 (17.8)30 (11.6)0.584 (0.324–1.000)0.0500.622 (0.350–1.108)0.10725 (11.5)0.622 (0.352–1.099)0.1020.660 (0.358–1.218)0.184
CC+TC vs TT 0.841 (0.590–1.199)0.3390.840 (0.574–1.229)0.369 0.948 (0.653–1.376)0.7790.946 (0.633–1.414)0.786
CC vs TC+TT 0.604 (0.368-0.992)0.0460.65 (0.381–1.109)0.114 0.597 (0.353–1.009)0.0540.641 (0.365–1.128)0.123
T allele307 (59.5)335 (64.7)1.00 (ref)   276 (63.3)1.00 (ref)   
C allele209 (40.5)183 (35.3)0.802 (0.624–1.032)0.086  160 (36.7)0.852 (0.655–1.107)0.230  
≤ 60           
TT108 (38.0)101 (40.7)1.00 (ref)   70 (40.0)1.00 (ref)   
TC138 (48.6)121 (48.8)0.938 (0.651–1.351)0.7291.079 (0.717–1.622)0.71686 (49.1)0.961 (0.642–1.440)0.8491.151 (0.730–1.815)0.544
CC38 (13.4)26 (10.5)0.732 (0.415–1.291)0.2810.660 (0.353–1.234)0.19319 (10.9)0.771 (0.412–1.445)0.4180.763 (0.383–1.521)0.443
CC+TC vs TT 0.893 (0.630–1.266)0.5250.976 (0.662–1.439)0.904 0.920 (0.626–1.354)0.6741.056 (0.685–1.628)0.805
CC vs TC+TT 0.758 (0.446–1.289)0.3070.633 (0.353–1.136)0.125 0.788 (0.439–1.417)0.4270.707 (0.372–1.342)0.288
T allele354 (62.3)323 (65.1)1.00 (ref)   226 (64.6)1.00 (ref)   
C allele214 (37.7)173 (34.9)0.886 (0.689–1.139)0.344  124 (35.4)0.908 (0.688–1.197)0.493  
  1. OR odds ratio, CI confidence interval, NSCLC non-small-cell lung cancer
  2. aAdjusted for age, gender, and smoking