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Table 3 ADRB1 haplotype and associated metoprolol clinical effect

From: Multiplex SNaPshot—a new simple and efficient CYP2D6 and ADRB1 genotyping method

ADRB1 haplotypes

Metoprolol clinical effect

49Ser389Arg/49Ser389Arg

Threefold greater diastolic blood pressure reduction [7, 12]

49Ser389Arg/49Gly389Arg

Good responder [12]

49Ser389Gly/49Gly389Arg and 49Ser389Gly/49Ser389Gly

Non-responders [7, 12]

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