Table 2 Clinical phenotype of FHM patient with mutation M1500V in exon 24 of SCN1A

Hemiplegic migraine (HM) onset (years)

22

Triggering factors of HM

Emotional stress

Hemiplegia during aura phase

+

Sensory disturbances during aura phase

+

Visual disturbances during aura phase

+

Aphasia during aura phase

+

Aura duration (min)

60

Headache duration (h)

4–24

Side of headache and hemiplegia

Bilateral—variable sides

Character

Pulsating

Nausea/vomiting/photophobia/phonophobia during migraine attack

+/−/−/−

Other types of headache

MO, MA