Reference | AD cases | No affected parents | FH- | FHm | FHp | Mother:father ratio |
---|
Heyman et al.[81] | 68 | 11 | 84% | 10% | 6% | 1.8:1 |
Duara et al.[77] | 311 | 69 | 78% | 17% | 5% | 3.6:1 |
Edland et al.[78] | 118 | 24 | 80% | 16% | 4% | 3.8:1 |
Farrer et al.[70] | 251 | 61 | 76% | 16% | 8% | 1.9:1 |
Gomez-Tortosa et al.[80] | 2594 | 817 | 68% | 23% | 9% | 2.6:1 |
- FH- = No family history of AD; FHm = maternal history of AD; FHp = paternal history of AD.