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Figure 2 | Human Genomics

Figure 2

From: Genome-wide characterisation of the binding repertoire of small molecule drugs

Figure 2

Structure of Hsp90 with bound geldamycin. Protein is rendered using colours to represent the similarity between the sequence of the protein and the sequences of peptides selected for affinity to Taxolâ„¢. Red indicates a high level of similarity, blue a very low level. Three segments with relatively high similarity scores bracket the geldamycin-binding site, suggesting that Taxolâ„¢ may bind to the same site

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